Analytical Chemist · Pharmaceutical HPLC, OQ/PQ & Quality Control

Mahdee Nafee
Muhammad

Turning samples into answers — chromatography, spectroscopy, and quality-driven method work, from the research bench to the regulated lab.

Columbia, Missouri M.S. Chemistry · Mizzou HPLC · OQ/PQ · cGMP/GLP
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The read

An analytical chemist who has run instruments on both sides of the bench — qualifying HPLC systems inside pharmaceutical plants, and characterizing air-sensitive actinide compounds in a research lab.

My work sits where careful measurement meets accountability: preparing samples and reagents, running and troubleshooting instruments, interpreting the data, and documenting all of it to the standard a regulated lab expects.

I'm completing an M.S. in Chemistry at the University of Missouri, building on hands-on pharmaceutical HPLC experience and graduate training across analytical, organic, and inorganic chemistry. I'm now focused on quality control — applying what I know and learning the systems around it.

1.5 yrPharma HPLC / OQ · PQ experience
15+Lab staff trained on HPLC
6Analytical techniques run routinely
Jan 2027Available full-time
IELTS 7.5English · CEFR C1
Experience

Where the work has been done

From industrial pharmaceutical sites to a synthetic actinide research group — a through-line of instruments, data, and documentation.

2023 — Present Walensky Lab
University of Missouri
Columbia, MO
Graduate Research Assistant
Inorganic & organometallic synthesis · analytical characterization
  • Characterize synthesized compounds by multinuclear NMR, single-crystal X-ray diffraction, FT-IR, UV-Vis, and fluorescence spectroscopy.
  • Run air-sensitive inorganic and organometallic synthesis using Schlenk-line and glovebox techniques under controlled conditions.
  • Prepare samples, solutions, and reagents; keep detailed records; analyze and interpret data across techniques.
  • Handle uranium- and thorium-containing materials under established safety procedures.
  • Troubleshoot procedures and instrumentation to improve reproducibility and data quality.
  • Manage multiple projects while maintaining accurate notebooks and chemical inventories.
Mar 2022 — Jul 2023 Medi-Graphic Trading Ltd.
Authorized Shimadzu Distributor
Dhaka, Bangladesh
Application Chemist
HPLC qualification & support inside pharmaceutical plants
  • Performed scheduled instrument calibration within OQ/PQ visits at customer sites, documented under cGMP.
  • Operated and supported HPLC instrumentation (Shimadzu Nexera LC-40 & Prominence) during qualification and performance verification.
  • Worked on-site in pharmaceutical QC, R&D, product-development, and cephalosporin labs at Beximco, Healthcare, Incepta, and Renata.
  • Diagnosed instrument and chromatography software issues on-site; resolved routine ones and escalated complex faults to IT/engineering.
  • Maintained OQ/PQ documentation and test records for labs under cGMP/GLP; supported Shimadzu LabSolutions CDS configuration.
  • Trained 15+ laboratory personnel on routine HPLC operation and chromatography software.
  • Observed GC operation and developed familiarity with GC instrumentation and workflows.
2020 — 2022 BCSIR · Refractory & Structural Ceramic Research Div.
Dhaka, Bangladesh
Graduate Researcher
Materials chemistry — synthesis & characterization
  • Conducted materials-chemistry research: synthesis, sample preparation, characterization, and data analysis.
  • Synthesized retarding admixtures and evaluated their effects on Ordinary Portland Cement.
  • Prepared reagents and samples and ran controlled experiments to evaluate material properties.
  • Analyzed and interpreted results; maintained detailed experimental documentation.
  • Built experience in laboratory safety, experimental design, troubleshooting, and reporting.
Jul 2019 — Dec 2020 The New School Dhaka (NSD)
Banani, Dhaka, Bangladesh
Chemistry Teacher
O-Level & A-Level chemistry, English-medium curriculum
  • Taught basic and advanced chemistry to O-Level (Edexcel) students and tutored A-Level (Cambridge) students.
  • Adapted instruction and pacing to individual student needs, sharpening clear communication of technical concepts to non-experts.
Technical skills

The full method set

Select a category to see the tools and techniques behind it.

Chromatography & analytical instrumentation

HPLC (Nexera LC-40 · Prominence)Instrument qualificationOQ / PQInstrument calibrationTitrations Chromatography data analysisInstrument troubleshootingFamiliarity with GC

Spectroscopic & structural characterization

Multinuclear NMRSingle-crystal XRDFT-IR UV-VisFluorescence spectroscopy

Laboratory techniques

Sample preparationStandard, solution & reagent prepAir-sensitive synthesis Schlenk-lineGlovebox operationsInorganic synthesis Organometallic synthesisActinide chemistry

Quality & documentation

SOP-driven workcGMP / GLPQualification protocols Laboratory documentationExperimental recordkeepingData review Performance verificationTroubleshootingLaboratory safety

Software

Shimadzu LabSolutionsWaters EmpowerThermo Chromeleon TopSpinMestReNovaOLEX2Mercury Cary WinUVOriginProExcel · Word · PowerPoint
Education & research

Training and published work

Expected Dec 2026

M.S. in Chemistry

University of Missouri — Columbia, MO
Advisor: Dr. Justin Walensky
Manuscripts in preparation
  1. Chalcogen Atom Transfer to Uranium(III) Bulky Amide Precursors.
  2. Synthesis & Characterization of a Novel 9-Borafluorene and Its Group 6 Isocyanido Pentacarbonyl-Capped Derivatives.
May 2022

M.S. in Organic Chemistry

University of Dhaka — Dhaka, Bangladesh
Advisor: Md. Ershad Halim, Ph.D.
Co-advisor: Dr. Umme Sarmeen Akhtar (BCSIR)
Publication · First author Synthesis & Characterization of Sodium Gluconate and Its Effects on the Properties of Portland Cement.
Int. Res. J. Pure Appl. Chem. 24(4), 20–32 (2023) · published as Nafee M. M. · cited in later peer-reviewed research
View publication (DOI)
Sep 2019

B.S. in Chemistry

University of Dhaka — Dhaka, Bangladesh
Advisor: Dr. Kawsari Akhter
Honors project Synthesis of α,β-Unsaturated Cyanoesters Using Substituted Benzaldehydes and Ethyl Cyanoacetate.
Contact

Let's talk quality control.

Available for full-time analytical / QC roles beginning January 2027. Happy to walk through my HPLC and qualification experience anytime.

LocationColumbia, Missouri
Work authorization & availability — January 2027